This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

安諾倫(北京)生物科技有限公司是一家創(chuàng)辦于2015年的創(chuàng)新型高科技企業(yè),公司由在國(guó)內(nèi)科研試劑領(lǐng)域有著十幾年從業(yè)經(jīng)驗(yàn)的專業(yè)技術(shù)團(tuán)隊(duì)和企業(yè)管理團(tuán)隊(duì)組建而成,專門從事以抗體、蛋白、細(xì)胞、化學(xué)品為核心的試劑產(chǎn)品研發(fā)與銷售。擁有國(guó)內(nèi)外數(shù)百家品牌試劑代理權(quán),為眾多需求客戶及科研機(jī)構(gòu)提供品質(zhì)保障、價(jià)格合理和操作便捷的品牌試劑。
我們的優(yōu)勢(shì)!
1、覆蓋歐美的全球采購(gòu)中心,擁有采購(gòu)團(tuán)隊(duì)數(shù)十人,進(jìn)口產(chǎn)品涵蓋抗體,蛋白,細(xì)胞,血清,耗材等的全門類生物產(chǎn)品。
2、代理貨品齊全,部分現(xiàn)貨,目前,與歐美數(shù)百家建立了正式的代理與合作,基本涵蓋所有的生物試劑門類,特別是二三線高質(zhì)量品牌產(chǎn)品,優(yōu)勢(shì)更大! 
3、更快捷的到貨時(shí)間,我們將以更短的訂貨周期,更快捷的國(guó)際物流以及報(bào)關(guān)時(shí)間為您提供時(shí)間的供貨保證(安諾倫具有獨(dú)立的進(jìn)出口和報(bào)關(guān)權(quán),因此提供更快捷的到貨保障)。
4、更高價(jià)格優(yōu)勢(shì)和性價(jià)比的選擇,我們將一如既往的為客戶和代理商提供*價(jià)格競(jìng)爭(zhēng)力的產(chǎn)品和全面的售后保障(作為中國(guó)區(qū)域代理,我們能提供最大的和更全面的技術(shù)支持)。